Martin Hetzer

Hetzer Group

79 Publications

Mark all

[79]
2024 | Journal Article | IST-REx-ID: 15316
Lifelong persistence of nuclear RNAs in the mouse brain
S. Zocher, A. Mccloskey, A. Karasinsky, R. Schulte, U. Friedrich, M. Lesche, N. Rund, F.H. Gage, M. Hetzer, T. Toda, Science 384 (2024) 53–59.
View | DOI | PubMed | Europe PMC
 
[78]
2023 | Journal Article | IST-REx-ID: 12880 | OA
Lamin B1 overexpression alters chromatin organization and gene expression
J.M. Kaneshiro, J.S. Capitanio, M. Hetzer, Nucleus 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[77]
2023 | Journal Article | IST-REx-ID: 14315 | OA
Caspase-mediated nuclear pore complex trimming in cell differentiation and endoplasmic reticulum stress
U.H. Cho, M. Hetzer, ELife 12 (2023).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[76]
2022 | Journal Article | IST-REx-ID: 11051
Nuclear pore complex maintenance and implications for age-related diseases
J. Liu, M. Hetzer, Trends in Cell Biology 32 (2022) P216-227.
View | DOI | PubMed | Europe PMC
 
[75]
2021 | Journal Article | IST-REx-ID: 11053 | OA
The San Diego Nathan Shock Center: Tackling the heterogeneity of aging
G.S. Shadel, P.D. Adams, W.T. Berggren, J.K. Diedrich, K.E. Diffenderfer, F.H. Gage, N. Hah, M. Hansen, M. Hetzer, A.J.A. Molina, U. Manor, K. Marek, D.D. O’Keefe, A.F.M. Pinto, A. Sacco, T.O. Sharpee, M.N. Shokriev, S. Zambetti, GeroScience 43 (2021) 2139–2148.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[74]
2021 | Journal Article | IST-REx-ID: 11052
Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
S. Krishna, R. Arrojo e Drigo, J.S. Capitanio, R. Ramachandra, M. Ellisman, M. Hetzer, Developmental Cell 56 (2021) P2952–2965.e9.
View | DOI | PubMed | Europe PMC
 
[73]
2020 | Journal Article | IST-REx-ID: 11056 | OA
Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease
S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced Biosystems 4 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[72]
2020 | Journal Article | IST-REx-ID: 11055 | OA
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[71]
2020 | Journal Article | IST-REx-ID: 11054 | OA
Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging
U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[70]
2020 | Journal Article | IST-REx-ID: 11057 | OA
Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation
H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes & Development 34 (2020) 913–930.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[69]
2020 | Journal Article | IST-REx-ID: 11058 | OA
Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling
S. Bersini, N.K. Lytle, R. Schulte, L. Huang, G.M. Wahl, M. Hetzer, Life Science Alliance 3 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[68]
2019 | Journal Article | IST-REx-ID: 11061 | OA
Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells
B.H. Toyama, R. Arrojo e Drigo, V. Lev-Ram, R. Ramachandra, T.J. Deerinck, C. Lechene, M.H. Ellisman, M. Hetzer, Journal of Cell Biology 218 (2019) 433–444.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[67]
2019 | Journal Article | IST-REx-ID: 11062 | OA
Age mosaicism across multiple scales in adult tissues
R. Arrojo e Drigo, V. Lev-Ram, S. Tyagi, R. Ramachandra, T. Deerinck, E. Bushong, S. Phan, V. Orphan, C. Lechene, M.H. Ellisman, M. Hetzer, Cell Metabolism 30 (2019) 343–351.e3.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[66]
2019 | Journal Article | IST-REx-ID: 11059
Coaching from the sidelines: The nuclear periphery in genome regulation
A. Buchwalter, J.M. Kaneshiro, M. Hetzer, Nature Reviews Genetics 20 (2019) 39–50.
View | DOI | PubMed | Europe PMC
 
[65]
2019 | Journal Article | IST-REx-ID: 11060 | OA
Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, ELife 8 (2019).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[64]
2019 | Research Data Reference | IST-REx-ID: 13079 | OA
Data from: Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, (2019).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
[63]
2018 | Journal Article | IST-REx-ID: 11063 | OA
Tpr regulates the total number of nuclear pore complexes per cell nucleus
A. McCloskey, A. Ibarra, M. Hetzer, Genes & Development 32 (2018) 1321–1331.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[62]
2018 | Journal Article | IST-REx-ID: 11064 | OA
Predicting age from the transcriptome of human dermal fibroblasts
J.G. Fleischer, R. Schulte, H.H. Tsai, S. Tyagi, A. Ibarra, M.N. Shokhirev, L. Huang, M. Hetzer, S. Navlakha, Genome Biology 19 (2018).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[61]
2017 | Journal Article | IST-REx-ID: 11066 | OA
Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells
T.M. Franks, A. McCloskey, M.N. Shokhirev, C. Benner, A. Rathore, M. Hetzer, Genes & Development 31 (2017) 2222–2234.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[60]
2017 | Journal Article | IST-REx-ID: 11067 | OA
Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells
T. Toda, J.Y. Hsu, S.B. Linker, L. Hu, S.T. Schafer, J. Mertens, F.V. Jacinto, M. Hetzer, F.H. Gage, Cell Stem Cell 21 (2017) 618–634.e7.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[59]
2017 | Journal Article | IST-REx-ID: 11065 | OA
Nucleolar expansion and elevated protein translation in premature aging
A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[58]
2016 | Journal Article | IST-REx-ID: 11072 | OA
p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis
R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[57]
2016 | Journal Article | IST-REx-ID: 11071 | OA
Evolution of a transcriptional regulator from a transmembrane nucleoporin
T.M. Franks, C. Benner, I. Narvaiza, M.C.N. Marchetto, J.M. Young, H.S. Malik, F.H. Gage, M. Hetzer, Genes & Development 30 (2016) 1155–1171.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[56]
2016 | Journal Article | IST-REx-ID: 11069 | OA
Nuclear envelope rupture is induced by actin-based nucleus confinement
E.M. Hatch, M. Hetzer, Journal of Cell Biology 215 (2016) 27–36.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[55]
2016 | Journal Article | IST-REx-ID: 11070 | OA
Nucleoporin-mediated regulation of cell identity genes
A. Ibarra, C. Benner, S. Tyagi, J. Cool, M. Hetzer, Genes & Development 30 (2016) 2253–2258.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[54]
2015 | Journal Article | IST-REx-ID: 11079 | OA
Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects
J. Mertens, A.C.M. Paquola, M. Ku, E. Hatch, L. Böhnke, S. Ladjevardi, S. McGrath, B. Campbell, H. Lee, J.R. Herdy, J.T. Gonçalves, T. Toda, Y. Kim, J. Winkler, J. Yao, M. Hetzer, F.H. Gage, Cell Stem Cell 17 (2015) 705–718.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[53]
2015 | Journal Article | IST-REx-ID: 11077 | OA
The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing
F.V. Jacinto, C. Benner, M. Hetzer, Genes & Development 29 (2015) 1224–1238.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[52]
2015 | Journal Article | IST-REx-ID: 11078 | OA
Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats
A. Ori, B.H. Toyama, M.S. Harris, T. Bock, M. Iskar, P. Bork, N.T. Ingolia, M. Hetzer, M. Beck, Cell Systems 1 (2015) P224-237.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[51]
2015 | Journal Article | IST-REx-ID: 11075
The nucleoporin gp210/Nup210 controls muscle differentiation by regulating nuclear envelope/ER homeostasis
J.S. Gomez-Cavazos, M. Hetzer, Journal of Cell Biology 208 (2015) 671–681.
[Published Version] View | DOI | PubMed | Europe PMC
 
[50]
2015 | Journal Article | IST-REx-ID: 11076 | OA
Nuclear pore proteins and the control of genome functions
A. Ibarra, M. Hetzer, Genes & Development 29 (2015) 337–349.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[49]
2015 | Journal Article | IST-REx-ID: 11073 | OA
Linking micronuclei to chromosome fragmentation
E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[48]
2015 | Journal Article | IST-REx-ID: 11074 | OA
Chromothripsis
E.M. Hatch, M. Hetzer, Current Biology 25 (2015) PR397-R399.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[47]
2014 | Journal Article | IST-REx-ID: 11080 | OA
Nuclear pores set the speed limit for mitosis
A. Buchwalter, M. Hetzer, Cell 156 (2014) 868–869.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[46]
2014 | Journal Article | IST-REx-ID: 11082 | OA
Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics
A.L. Buchwalter, Y. Liang, M. Hetzer, Molecular Biology of the Cell 25 (2014) 2472–2484.
[Published Version] View | DOI | Download Published Version (ext.)
 
[45]
2014 | Journal Article | IST-REx-ID: 11081 | OA
Breaching the nuclear envelope in development and disease
E. Hatch, M. Hetzer, Journal of Cell Biology 205 (2014) 133–141.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[44]
2013 | Journal Article | IST-REx-ID: 11086 | OA
Dynamic association of NUP98 with the human genome
Y. Liang, T.M. Franks, M.C. Marchetto, F.H. Gage, M. Hetzer, PLoS Genetics 9 (2013).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[43]
2013 | Journal Article | IST-REx-ID: 11087 | OA
Identification of long-lived proteins reveals exceptional stability of essential cellular structures
B.H. Toyama, J.N. Savas, S.K. Park, M.S. Harris, N.T. Ingolia, J.R. Yates, M. Hetzer, Cell 154 (2013) 971–982.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[42]
2013 | Journal Article | IST-REx-ID: 11085 | OA
Catastrophic nuclear envelope collapse in cancer cell micronuclei
E.M. Hatch, A.H. Fischer, T.J. Deerinck, M. Hetzer, Cell 154 (2013) 47–60.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[41]
2013 | Journal Article | IST-REx-ID: 11088 | OA
Anomalous diffusion of single particles in cytoplasm
B.M. Regner, D. Vučinić, C. Domnisoru, T.M. Bartol, M. Hetzer, D.M. Tartakovsky, T.J. Sejnowski, Biophysical Journal 104 (2013) 1652–1660.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[40]
2013 | Journal Article | IST-REx-ID: 11083
The role of Nup98 in transcription regulation in healthy and diseased cells
T.M. Franks, M. Hetzer, Trends in Cell Biology 23 (2013) 112–117.
View | DOI | PubMed | Europe PMC
 
[39]
2013 | Journal Article | IST-REx-ID: 11084
Protein homeostasis: Live long, won't prosper
B.H. Toyama, M. Hetzer, Nature Reviews Molecular Cell Biology 14 (2013) 55–61.
View | DOI | PubMed | Europe PMC
 
[38]
2012 | Journal Article | IST-REx-ID: 11089
Outfits for different occasions: tissue-specific roles of Nuclear Envelope proteins
J.S. Gomez-Cavazos, M. Hetzer, Current Opinion in Cell Biology 24 (2012) 775–783.
View | DOI | PubMed | Europe PMC
 
[37]
2012 | Journal Article | IST-REx-ID: 11091
Transient nuclear envelope rupturing during interphase in human cancer cells
J.D. Vargas, E.M. Hatch, D.J. Anderson, M. Hetzer, Nucleus 3 (2012) 88–100.
View | DOI | PubMed | Europe PMC
 
[36]
2012 | Journal Article | IST-REx-ID: 11093 | OA
A change in nuclear pore complex composition regulates cell differentiation
M.A. D’Angelo, J.S. Gomez-Cavazos, A. Mei, D.H. Lackner, M. Hetzer, Developmental Cell 22 (2012) 446–458.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[35]
2012 | Journal Article | IST-REx-ID: 11092
Extremely long-lived nuclear pore proteins in the rat brain
J.N. Savas, B.H. Toyama, T. Xu, J.R. Yates, M. Hetzer, Science 335 (2012) 942–942.
View | DOI | PubMed | Europe PMC
 
[34]
2012 | Journal Article | IST-REx-ID: 11090 | OA
RNP export by nuclear envelope budding
E.M. Hatch, M. Hetzer, Cell 149 (2012) 733–735.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[33]
2011 | Journal Article | IST-REx-ID: 11094 | OA
POM121 and Sun1 play a role in early steps of interphase NPC assembly
J.A. Talamas, M. Hetzer, Journal of Cell Biology 194 (2011) 27–37.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[32]
2011 | Journal Article | IST-REx-ID: 11096
Functional interactions between nucleoporins and chromatin
Y. Liang, M. Hetzer, Current Opinion in Cell Biology 23 (2011) 65–70.
View | DOI | PubMed | Europe PMC
 
[31]
2011 | Journal Article | IST-REx-ID: 11095
Editorial overview
M. Hetzer, G. Cavalli, Current Opinion in Cell Biology 23 (2011) 255–257.
View | DOI | PubMed | Europe PMC
 
[30]
2011 | Journal Article | IST-REx-ID: 11100
Nuclear pore complexes: Guardians of the nuclear genome
M. Capelson, C. Doucet, M. Hetzer, Cold Spring Harbor Symposia on Quantitative Biology 75 (2011) 585–597.
View | DOI | PubMed | Europe PMC
 
[29]
2010 | Journal Article | IST-REx-ID: 11097
The nuclear envelope
M. Hetzer, Cold Spring Harbor Perspectives in Biology 2 (2010) a000539–a000539.
View | DOI | PubMed | Europe PMC
 
[28]
2010 | Journal Article | IST-REx-ID: 11099
Nuclear pore biogenesis into an intact nuclear envelope
C.M. Doucet, M. Hetzer, Chromosoma 119 (2010) 469–477.
View | DOI | PubMed | Europe PMC
 
[27]
2010 | Journal Article | IST-REx-ID: 11102 | OA
Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, M. Hetzer, Cell 140 (2010) 372–383.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[26]
2010 | Journal Article | IST-REx-ID: 11101 | OA
Cell cycle-dependent differences in nuclear pore complex assembly in metazoa
C.M. Doucet, J.A. Talamas, M. Hetzer, Cell 141 (2010) 1030–1041.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[25]
2010 | Journal Article | IST-REx-ID: 11098 | OA
The role of the nuclear pore complex in aging of post-mitotic cells
M. Hetzer, Aging 2 (2010) 74–75.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[24]
2009 | Journal Article | IST-REx-ID: 11103 | OA
Border control at the nucleus: Biogenesis and organization of the nuclear membrane and pore complexes
M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[23]
2009 | Journal Article | IST-REx-ID: 11106 | OA
Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo
D.J. Anderson, J.D. Vargas, J.P. Hsiao, M. Hetzer, Journal of Cell Biology 186 (2009) 183–191.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[22]
2009 | Journal Article | IST-REx-ID: 11107 | OA
ER membrane–bending proteins are necessary for de novo nuclear pore formation
T.R. Dawson, M.D. Lazarus, M. Hetzer, S.R. Wente, Journal of Cell Biology 184 (2009) 659–675.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[21]
2009 | Journal Article | IST-REx-ID: 11108 | OA
Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells
M.A. D’Angelo, M. Raices, S.H. Panowski, M. Hetzer, Cell 136 (2009) 284–295.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[20]
2009 | Journal Article | IST-REx-ID: 11105 | OA
The role of nuclear pores in gene regulation, development and disease
M. Capelson, M. Hetzer, EMBO Reports 10 (2009) 697–705.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[19]
2008 | Journal Article | IST-REx-ID: 11111
Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation
D.J. Anderson, M. Hetzer, Journal of Cell Biology 182 (2008) 911–924.
View | DOI | PubMed | Europe PMC
 
[18]
2008 | Journal Article | IST-REx-ID: 11110
Structure, dynamics and function of nuclear pore complexes
M.A. D’Angelo, M. Hetzer, Trends in Cell Biology 18 (2008) 456–466.
View | DOI | PubMed | Europe PMC
 
[17]
2008 | Journal Article | IST-REx-ID: 11109
Reorganization of the nuclear envelope during open mitosis
U. Kutay, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 669–677.
View | DOI | PubMed | Europe PMC
 
[16]
2008 | Journal Article | IST-REx-ID: 11112
The life cycle of the metazoan nuclear envelope
D.J. Anderson, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 386–392.
View | DOI | PubMed | Europe PMC
 
[15]
2008 | Journal Article | IST-REx-ID: 11113 | OA
Shaping the endoplasmic reticulum into the nuclear envelope
D.J. Anderson, M. Hetzer, Journal of Cell Science 121 (2008) 137–142.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2008 | Journal Article | IST-REx-ID: 11114 | OA
Single bead affinity detection (SINBAD) for the analysis of protein-protein interactions
R. Schulte, J. Talamas, C. Doucet, M. Hetzer, PLoS ONE 3 (2008).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[13]
2007 | Journal Article | IST-REx-ID: 11116 | OA
MEL‐28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly
C. Franz, R. Walczak, S. Yavuz, R. Santarella, M. Gentzel, P. Askjaer, V. Galy, M. Hetzer, I.W. Mattaj, W. Antonin, EMBO Reports 8 (2007) 165–172.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[12]
2007 | Journal Article | IST-REx-ID: 11115
Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum
D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166.
View | DOI | PubMed | Europe PMC
 
[11]
2006 | Book Chapter | IST-REx-ID: 11119
In Vitro Techniques
Harris JR, Almouzni G, Kirschner D, Dimitrova D, Nickerson JA, Underwood J, Wagner S, Korbei B, Foisner R, Walther TC, Hetzer M, Peters R, Walev I, de Kroon AIPM, Staffhorst RWHM, de Kruijff B, Burger KNJ, Netto LES, Bertrand E, Alimonti JB, Greenberg AH, Xiao J, Pradhan A, Liu Y, Paiement J, Young R, Goñi FM, Villar A-V, Contreras F-X, Alonso A, Peter BJ, Mills IG, Higgins MK, Brown WJ, Chambers K, Doody A, Cheng CY, Mruk DD, Yang C, Kirchhoff H, Haase W, Boggasch S, Paulsen H, Benesova J, Liffers S-T, Rögner M, Gao Y, Sztul E, Thiemann M, Fahimi HD, Gniadecki R, Gajkowska B, Bane SL, Hess JF, Voss JC, Fitzgerald PG, Hisanaga S, Sasaki T, Uéda K, Town T, Tan J, Milton NGN, Chi R, Keller TCS, Kriajevska M, Bronstein I, Lukanidin E, Holmes DF, Kadler KE. 2006.In Vitro Techniques. In: Cell Biology Protocols. , 201–378.
View | DOI
 
[10]
2006 | Journal Article | IST-REx-ID: 11117
The role of the nuclear envelope in cellular organization
M.A. D’Angelo, M. Hetzer, Cellular and Molecular Life Sciences 63 (2006) 316–332.
View | DOI | PubMed | Europe PMC
 
[9]
2006 | Journal Article | IST-REx-ID: 11118
Nuclear pores form de novo from both sides of the nuclear envelope
M.A. D’Angelo, D.J. Anderson, E. Richard, M. Hetzer, Science 312 (2006) 440–443.
View | DOI | PubMed | Europe PMC
 
[8]
2005 | Journal Article | IST-REx-ID: 11120
Pushing the envelope: Structure, function, and dynamics of the nuclear periphery
M. Hetzer, T.C. Walther, I.W. Mattaj, Annual Review of Cell and Developmental Biology 21 (2005) 347–380.
View | DOI | PubMed | Europe PMC
 
[7]
2003 | Journal Article | IST-REx-ID: 11122
The conserved Nup107-160 complex is critical for nuclear pore complex assembly
T.C. Walther, A. Alves, H. Pickersgill, I. Loı̈odice, M. Hetzer, V. Galy, B.B. Hülsmann, T. Köcher, M. Wilm, T. Allen, I.W. Mattaj, V. Doye, Cell 113 (2003) 195–206.
[Published Version] View | DOI | PubMed | Europe PMC
 
[6]
2003 | Journal Article | IST-REx-ID: 11121
RanGTP mediates nuclear pore complex assembly
T.C. Walther, P. Askjaer, M. Gentzel, A. Habermann, G. Griffiths, M. Wilm, I.W. Mattaj, M. Hetzer, Nature 424 (2003) 689–694.
View | DOI | PubMed | Europe PMC
 
[5]
2002 | Journal Article | IST-REx-ID: 11124 | OA
Ran binds to chromatin by two distinct mechanisms
D. Bilbao-Cortés, M. Hetzer, G. Längst, P.B. Becker, I.W. Mattaj, Current Biology 12 (2002) 1151–1156.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[4]
2002 | Journal Article | IST-REx-ID: 11123
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) E177–E184.
View | DOI | PubMed | Europe PMC
 
[3]
2001 | Journal Article | IST-REx-ID: 11125
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly
M. Hetzer, H.H. Meyer, T.C. Walther, D. Bilbao-Cortes, G. Warren, I.W. Mattaj, Nature Cell Biology 3 (2001) 1086–1091.
View | DOI | PubMed | Europe PMC
 
[2]
2000 | Journal Article | IST-REx-ID: 11126
An Atp-dependent, Ran-independent mechanism for nuclear import of the U1a and U2b′′ spliceosome proteins
M. Hetzer, I.W. Mattaj, Journal of Cell Biology 148 (2000) 293–304.
View | DOI | PubMed | Europe PMC
 
[1]
2000 | Journal Article | IST-REx-ID: 11127 | OA
GTP hydrolysis by Ran is required for nuclear envelope assembly
M. Hetzer, D. Bilbao-Cortés, T.C. Walther, O.J. Gruss, I.W. Mattaj, Molecular Cell 5 (2000) 1013–1024.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
Marked Publication(s)

Search

Filter Publications

    • Display / Sort

    Citation Style: Default

    Export / Embed

79 Publications

Mark all

[79]
2024 | Journal Article | IST-REx-ID: 15316
Lifelong persistence of nuclear RNAs in the mouse brain
S. Zocher, A. Mccloskey, A. Karasinsky, R. Schulte, U. Friedrich, M. Lesche, N. Rund, F.H. Gage, M. Hetzer, T. Toda, Science 384 (2024) 53–59.
View | DOI | PubMed | Europe PMC
 
[78]
2023 | Journal Article | IST-REx-ID: 12880 | OA
Lamin B1 overexpression alters chromatin organization and gene expression
J.M. Kaneshiro, J.S. Capitanio, M. Hetzer, Nucleus 14 (2023).
[Published Version] View | Files available | DOI | WoS | PubMed | Europe PMC
 
[77]
2023 | Journal Article | IST-REx-ID: 14315 | OA
Caspase-mediated nuclear pore complex trimming in cell differentiation and endoplasmic reticulum stress
U.H. Cho, M. Hetzer, ELife 12 (2023).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[76]
2022 | Journal Article | IST-REx-ID: 11051
Nuclear pore complex maintenance and implications for age-related diseases
J. Liu, M. Hetzer, Trends in Cell Biology 32 (2022) P216-227.
View | DOI | PubMed | Europe PMC
 
[75]
2021 | Journal Article | IST-REx-ID: 11053 | OA
The San Diego Nathan Shock Center: Tackling the heterogeneity of aging
G.S. Shadel, P.D. Adams, W.T. Berggren, J.K. Diedrich, K.E. Diffenderfer, F.H. Gage, N. Hah, M. Hansen, M. Hetzer, A.J.A. Molina, U. Manor, K. Marek, D.D. O’Keefe, A.F.M. Pinto, A. Sacco, T.O. Sharpee, M.N. Shokriev, S. Zambetti, GeroScience 43 (2021) 2139–2148.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[74]
2021 | Journal Article | IST-REx-ID: 11052
Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
S. Krishna, R. Arrojo e Drigo, J.S. Capitanio, R. Ramachandra, M. Ellisman, M. Hetzer, Developmental Cell 56 (2021) P2952–2965.e9.
View | DOI | PubMed | Europe PMC
 
[73]
2020 | Journal Article | IST-REx-ID: 11056 | OA
Transcriptional and functional changes of the human microvasculature during physiological aging and Alzheimer disease
S. Bersini, R. Arrojo e Drigo, L. Huang, M.N. Shokhirev, M. Hetzer, Advanced Biosystems 4 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[72]
2020 | Journal Article | IST-REx-ID: 11055 | OA
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome
S. Bersini, R. Schulte, L. Huang, H. Tsai, M. Hetzer, ELife 9 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[71]
2020 | Journal Article | IST-REx-ID: 11054 | OA
Nuclear periphery takes center stage: The role of nuclear pore complexes in cell identity and aging
U.H. Cho, M. Hetzer, Neuron 106 (2020) 899–911.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[70]
2020 | Journal Article | IST-REx-ID: 11057 | OA
Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation
H. Kang, M.N. Shokhirev, Z. Xu, S. Chandran, J.R. Dixon, M. Hetzer, Genes & Development 34 (2020) 913–930.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[69]
2020 | Journal Article | IST-REx-ID: 11058 | OA
Nup93 regulates breast tumor growth by modulating cell proliferation and actin cytoskeleton remodeling
S. Bersini, N.K. Lytle, R. Schulte, L. Huang, G.M. Wahl, M. Hetzer, Life Science Alliance 3 (2020).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[68]
2019 | Journal Article | IST-REx-ID: 11061 | OA
Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells
B.H. Toyama, R. Arrojo e Drigo, V. Lev-Ram, R. Ramachandra, T.J. Deerinck, C. Lechene, M.H. Ellisman, M. Hetzer, Journal of Cell Biology 218 (2019) 433–444.
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[67]
2019 | Journal Article | IST-REx-ID: 11062 | OA
Age mosaicism across multiple scales in adult tissues
R. Arrojo e Drigo, V. Lev-Ram, S. Tyagi, R. Ramachandra, T. Deerinck, E. Bushong, S. Phan, V. Orphan, C. Lechene, M.H. Ellisman, M. Hetzer, Cell Metabolism 30 (2019) 343–351.e3.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[66]
2019 | Journal Article | IST-REx-ID: 11059
Coaching from the sidelines: The nuclear periphery in genome regulation
A. Buchwalter, J.M. Kaneshiro, M. Hetzer, Nature Reviews Genetics 20 (2019) 39–50.
View | DOI | PubMed | Europe PMC
 
[65]
2019 | Journal Article | IST-REx-ID: 11060 | OA
Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, ELife 8 (2019).
[Published Version] View | Files available | DOI | PubMed | Europe PMC
 
[64]
2019 | Research Data Reference | IST-REx-ID: 13079 | OA
Data from: Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
A. Buchwalter, R. Schulte, H. Tsai, J. Capitanio, M. Hetzer, (2019).
[Published Version] View | Files available | DOI | Download Published Version (ext.)
 
[63]
2018 | Journal Article | IST-REx-ID: 11063 | OA
Tpr regulates the total number of nuclear pore complexes per cell nucleus
A. McCloskey, A. Ibarra, M. Hetzer, Genes & Development 32 (2018) 1321–1331.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[62]
2018 | Journal Article | IST-REx-ID: 11064 | OA
Predicting age from the transcriptome of human dermal fibroblasts
J.G. Fleischer, R. Schulte, H.H. Tsai, S. Tyagi, A. Ibarra, M.N. Shokhirev, L. Huang, M. Hetzer, S. Navlakha, Genome Biology 19 (2018).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[61]
2017 | Journal Article | IST-REx-ID: 11066 | OA
Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells
T.M. Franks, A. McCloskey, M.N. Shokhirev, C. Benner, A. Rathore, M. Hetzer, Genes & Development 31 (2017) 2222–2234.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[60]
2017 | Journal Article | IST-REx-ID: 11067 | OA
Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells
T. Toda, J.Y. Hsu, S.B. Linker, L. Hu, S.T. Schafer, J. Mertens, F.V. Jacinto, M. Hetzer, F.H. Gage, Cell Stem Cell 21 (2017) 618–634.e7.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[59]
2017 | Journal Article | IST-REx-ID: 11065 | OA
Nucleolar expansion and elevated protein translation in premature aging
A. Buchwalter, M. Hetzer, Nature Communications 8 (2017).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[58]
2016 | Journal Article | IST-REx-ID: 11072 | OA
p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis
R.A.H. van de Ven, J.S. de Groot, D. Park, R. van Domselaar, D. de Jong, K. Szuhai, E. van der Wall, O.M. Rueda, H.R. Ali, C. Caldas, P.J. van Diest, M. Hetzer, E. Sahai, P.W.B. Derksen, Nature Communications 7 (2016).
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[57]
2016 | Journal Article | IST-REx-ID: 11071 | OA
Evolution of a transcriptional regulator from a transmembrane nucleoporin
T.M. Franks, C. Benner, I. Narvaiza, M.C.N. Marchetto, J.M. Young, H.S. Malik, F.H. Gage, M. Hetzer, Genes & Development 30 (2016) 1155–1171.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[56]
2016 | Journal Article | IST-REx-ID: 11069 | OA
Nuclear envelope rupture is induced by actin-based nucleus confinement
E.M. Hatch, M. Hetzer, Journal of Cell Biology 215 (2016) 27–36.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[55]
2016 | Journal Article | IST-REx-ID: 11070 | OA
Nucleoporin-mediated regulation of cell identity genes
A. Ibarra, C. Benner, S. Tyagi, J. Cool, M. Hetzer, Genes & Development 30 (2016) 2253–2258.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[54]
2015 | Journal Article | IST-REx-ID: 11079 | OA
Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects
J. Mertens, A.C.M. Paquola, M. Ku, E. Hatch, L. Böhnke, S. Ladjevardi, S. McGrath, B. Campbell, H. Lee, J.R. Herdy, J.T. Gonçalves, T. Toda, Y. Kim, J. Winkler, J. Yao, M. Hetzer, F.H. Gage, Cell Stem Cell 17 (2015) 705–718.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[53]
2015 | Journal Article | IST-REx-ID: 11077 | OA
The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing
F.V. Jacinto, C. Benner, M. Hetzer, Genes & Development 29 (2015) 1224–1238.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[52]
2015 | Journal Article | IST-REx-ID: 11078 | OA
Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats
A. Ori, B.H. Toyama, M.S. Harris, T. Bock, M. Iskar, P. Bork, N.T. Ingolia, M. Hetzer, M. Beck, Cell Systems 1 (2015) P224-237.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[51]
2015 | Journal Article | IST-REx-ID: 11075
The nucleoporin gp210/Nup210 controls muscle differentiation by regulating nuclear envelope/ER homeostasis
J.S. Gomez-Cavazos, M. Hetzer, Journal of Cell Biology 208 (2015) 671–681.
[Published Version] View | DOI | PubMed | Europe PMC
 
[50]
2015 | Journal Article | IST-REx-ID: 11076 | OA
Nuclear pore proteins and the control of genome functions
A. Ibarra, M. Hetzer, Genes & Development 29 (2015) 337–349.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[49]
2015 | Journal Article | IST-REx-ID: 11073 | OA
Linking micronuclei to chromosome fragmentation
E.M. Hatch, M. Hetzer, Cell 161 (2015) 1502–1504.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[48]
2015 | Journal Article | IST-REx-ID: 11074 | OA
Chromothripsis
E.M. Hatch, M. Hetzer, Current Biology 25 (2015) PR397-R399.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[47]
2014 | Journal Article | IST-REx-ID: 11080 | OA
Nuclear pores set the speed limit for mitosis
A. Buchwalter, M. Hetzer, Cell 156 (2014) 868–869.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[46]
2014 | Journal Article | IST-REx-ID: 11082 | OA
Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics
A.L. Buchwalter, Y. Liang, M. Hetzer, Molecular Biology of the Cell 25 (2014) 2472–2484.
[Published Version] View | DOI | Download Published Version (ext.)
 
[45]
2014 | Journal Article | IST-REx-ID: 11081 | OA
Breaching the nuclear envelope in development and disease
E. Hatch, M. Hetzer, Journal of Cell Biology 205 (2014) 133–141.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[44]
2013 | Journal Article | IST-REx-ID: 11086 | OA
Dynamic association of NUP98 with the human genome
Y. Liang, T.M. Franks, M.C. Marchetto, F.H. Gage, M. Hetzer, PLoS Genetics 9 (2013).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[43]
2013 | Journal Article | IST-REx-ID: 11087 | OA
Identification of long-lived proteins reveals exceptional stability of essential cellular structures
B.H. Toyama, J.N. Savas, S.K. Park, M.S. Harris, N.T. Ingolia, J.R. Yates, M. Hetzer, Cell 154 (2013) 971–982.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[42]
2013 | Journal Article | IST-REx-ID: 11085 | OA
Catastrophic nuclear envelope collapse in cancer cell micronuclei
E.M. Hatch, A.H. Fischer, T.J. Deerinck, M. Hetzer, Cell 154 (2013) 47–60.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[41]
2013 | Journal Article | IST-REx-ID: 11088 | OA
Anomalous diffusion of single particles in cytoplasm
B.M. Regner, D. Vučinić, C. Domnisoru, T.M. Bartol, M. Hetzer, D.M. Tartakovsky, T.J. Sejnowski, Biophysical Journal 104 (2013) 1652–1660.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[40]
2013 | Journal Article | IST-REx-ID: 11083
The role of Nup98 in transcription regulation in healthy and diseased cells
T.M. Franks, M. Hetzer, Trends in Cell Biology 23 (2013) 112–117.
View | DOI | PubMed | Europe PMC
 
[39]
2013 | Journal Article | IST-REx-ID: 11084
Protein homeostasis: Live long, won't prosper
B.H. Toyama, M. Hetzer, Nature Reviews Molecular Cell Biology 14 (2013) 55–61.
View | DOI | PubMed | Europe PMC
 
[38]
2012 | Journal Article | IST-REx-ID: 11089
Outfits for different occasions: tissue-specific roles of Nuclear Envelope proteins
J.S. Gomez-Cavazos, M. Hetzer, Current Opinion in Cell Biology 24 (2012) 775–783.
View | DOI | PubMed | Europe PMC
 
[37]
2012 | Journal Article | IST-REx-ID: 11091
Transient nuclear envelope rupturing during interphase in human cancer cells
J.D. Vargas, E.M. Hatch, D.J. Anderson, M. Hetzer, Nucleus 3 (2012) 88–100.
View | DOI | PubMed | Europe PMC
 
[36]
2012 | Journal Article | IST-REx-ID: 11093 | OA
A change in nuclear pore complex composition regulates cell differentiation
M.A. D’Angelo, J.S. Gomez-Cavazos, A. Mei, D.H. Lackner, M. Hetzer, Developmental Cell 22 (2012) 446–458.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[35]
2012 | Journal Article | IST-REx-ID: 11092
Extremely long-lived nuclear pore proteins in the rat brain
J.N. Savas, B.H. Toyama, T. Xu, J.R. Yates, M. Hetzer, Science 335 (2012) 942–942.
View | DOI | PubMed | Europe PMC
 
[34]
2012 | Journal Article | IST-REx-ID: 11090 | OA
RNP export by nuclear envelope budding
E.M. Hatch, M. Hetzer, Cell 149 (2012) 733–735.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[33]
2011 | Journal Article | IST-REx-ID: 11094 | OA
POM121 and Sun1 play a role in early steps of interphase NPC assembly
J.A. Talamas, M. Hetzer, Journal of Cell Biology 194 (2011) 27–37.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[32]
2011 | Journal Article | IST-REx-ID: 11096
Functional interactions between nucleoporins and chromatin
Y. Liang, M. Hetzer, Current Opinion in Cell Biology 23 (2011) 65–70.
View | DOI | PubMed | Europe PMC
 
[31]
2011 | Journal Article | IST-REx-ID: 11095
Editorial overview
M. Hetzer, G. Cavalli, Current Opinion in Cell Biology 23 (2011) 255–257.
View | DOI | PubMed | Europe PMC
 
[30]
2011 | Journal Article | IST-REx-ID: 11100
Nuclear pore complexes: Guardians of the nuclear genome
M. Capelson, C. Doucet, M. Hetzer, Cold Spring Harbor Symposia on Quantitative Biology 75 (2011) 585–597.
View | DOI | PubMed | Europe PMC
 
[29]
2010 | Journal Article | IST-REx-ID: 11097
The nuclear envelope
M. Hetzer, Cold Spring Harbor Perspectives in Biology 2 (2010) a000539–a000539.
View | DOI | PubMed | Europe PMC
 
[28]
2010 | Journal Article | IST-REx-ID: 11099
Nuclear pore biogenesis into an intact nuclear envelope
C.M. Doucet, M. Hetzer, Chromosoma 119 (2010) 469–477.
View | DOI | PubMed | Europe PMC
 
[27]
2010 | Journal Article | IST-REx-ID: 11102 | OA
Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
M. Capelson, Y. Liang, R. Schulte, W. Mair, U. Wagner, M. Hetzer, Cell 140 (2010) 372–383.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[26]
2010 | Journal Article | IST-REx-ID: 11101 | OA
Cell cycle-dependent differences in nuclear pore complex assembly in metazoa
C.M. Doucet, J.A. Talamas, M. Hetzer, Cell 141 (2010) 1030–1041.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[25]
2010 | Journal Article | IST-REx-ID: 11098 | OA
The role of the nuclear pore complex in aging of post-mitotic cells
M. Hetzer, Aging 2 (2010) 74–75.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[24]
2009 | Journal Article | IST-REx-ID: 11103 | OA
Border control at the nucleus: Biogenesis and organization of the nuclear membrane and pore complexes
M. Hetzer, S.R. Wente, Developmental Cell 17 (2009) 606–616.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[23]
2009 | Journal Article | IST-REx-ID: 11106 | OA
Recruitment of functionally distinct membrane proteins to chromatin mediates nuclear envelope formation in vivo
D.J. Anderson, J.D. Vargas, J.P. Hsiao, M. Hetzer, Journal of Cell Biology 186 (2009) 183–191.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[22]
2009 | Journal Article | IST-REx-ID: 11107 | OA
ER membrane–bending proteins are necessary for de novo nuclear pore formation
T.R. Dawson, M.D. Lazarus, M. Hetzer, S.R. Wente, Journal of Cell Biology 184 (2009) 659–675.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[21]
2009 | Journal Article | IST-REx-ID: 11108 | OA
Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells
M.A. D’Angelo, M. Raices, S.H. Panowski, M. Hetzer, Cell 136 (2009) 284–295.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[20]
2009 | Journal Article | IST-REx-ID: 11105 | OA
The role of nuclear pores in gene regulation, development and disease
M. Capelson, M. Hetzer, EMBO Reports 10 (2009) 697–705.
[Published Version] View | Files available | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[19]
2008 | Journal Article | IST-REx-ID: 11111
Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation
D.J. Anderson, M. Hetzer, Journal of Cell Biology 182 (2008) 911–924.
View | DOI | PubMed | Europe PMC
 
[18]
2008 | Journal Article | IST-REx-ID: 11110
Structure, dynamics and function of nuclear pore complexes
M.A. D’Angelo, M. Hetzer, Trends in Cell Biology 18 (2008) 456–466.
View | DOI | PubMed | Europe PMC
 
[17]
2008 | Journal Article | IST-REx-ID: 11109
Reorganization of the nuclear envelope during open mitosis
U. Kutay, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 669–677.
View | DOI | PubMed | Europe PMC
 
[16]
2008 | Journal Article | IST-REx-ID: 11112
The life cycle of the metazoan nuclear envelope
D.J. Anderson, M. Hetzer, Current Opinion in Cell Biology 20 (2008) 386–392.
View | DOI | PubMed | Europe PMC
 
[15]
2008 | Journal Article | IST-REx-ID: 11113 | OA
Shaping the endoplasmic reticulum into the nuclear envelope
D.J. Anderson, M. Hetzer, Journal of Cell Science 121 (2008) 137–142.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[14]
2008 | Journal Article | IST-REx-ID: 11114 | OA
Single bead affinity detection (SINBAD) for the analysis of protein-protein interactions
R. Schulte, J. Talamas, C. Doucet, M. Hetzer, PLoS ONE 3 (2008).
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[13]
2007 | Journal Article | IST-REx-ID: 11116 | OA
MEL‐28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly
C. Franz, R. Walczak, S. Yavuz, R. Santarella, M. Gentzel, P. Askjaer, V. Galy, M. Hetzer, I.W. Mattaj, W. Antonin, EMBO Reports 8 (2007) 165–172.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[12]
2007 | Journal Article | IST-REx-ID: 11115
Nuclear envelope formation by chromatin-mediated reorganization of the endoplasmic reticulum
D.J. Anderson, M. Hetzer, Nature Cell Biology 9 (2007) 1160–1166.
View | DOI | PubMed | Europe PMC
 
[11]
2006 | Book Chapter | IST-REx-ID: 11119
In Vitro Techniques
Harris JR, Almouzni G, Kirschner D, Dimitrova D, Nickerson JA, Underwood J, Wagner S, Korbei B, Foisner R, Walther TC, Hetzer M, Peters R, Walev I, de Kroon AIPM, Staffhorst RWHM, de Kruijff B, Burger KNJ, Netto LES, Bertrand E, Alimonti JB, Greenberg AH, Xiao J, Pradhan A, Liu Y, Paiement J, Young R, Goñi FM, Villar A-V, Contreras F-X, Alonso A, Peter BJ, Mills IG, Higgins MK, Brown WJ, Chambers K, Doody A, Cheng CY, Mruk DD, Yang C, Kirchhoff H, Haase W, Boggasch S, Paulsen H, Benesova J, Liffers S-T, Rögner M, Gao Y, Sztul E, Thiemann M, Fahimi HD, Gniadecki R, Gajkowska B, Bane SL, Hess JF, Voss JC, Fitzgerald PG, Hisanaga S, Sasaki T, Uéda K, Town T, Tan J, Milton NGN, Chi R, Keller TCS, Kriajevska M, Bronstein I, Lukanidin E, Holmes DF, Kadler KE. 2006.In Vitro Techniques. In: Cell Biology Protocols. , 201–378.
View | DOI
 
[10]
2006 | Journal Article | IST-REx-ID: 11117
The role of the nuclear envelope in cellular organization
M.A. D’Angelo, M. Hetzer, Cellular and Molecular Life Sciences 63 (2006) 316–332.
View | DOI | PubMed | Europe PMC
 
[9]
2006 | Journal Article | IST-REx-ID: 11118
Nuclear pores form de novo from both sides of the nuclear envelope
M.A. D’Angelo, D.J. Anderson, E. Richard, M. Hetzer, Science 312 (2006) 440–443.
View | DOI | PubMed | Europe PMC
 
[8]
2005 | Journal Article | IST-REx-ID: 11120
Pushing the envelope: Structure, function, and dynamics of the nuclear periphery
M. Hetzer, T.C. Walther, I.W. Mattaj, Annual Review of Cell and Developmental Biology 21 (2005) 347–380.
View | DOI | PubMed | Europe PMC
 
[7]
2003 | Journal Article | IST-REx-ID: 11122
The conserved Nup107-160 complex is critical for nuclear pore complex assembly
T.C. Walther, A. Alves, H. Pickersgill, I. Loı̈odice, M. Hetzer, V. Galy, B.B. Hülsmann, T. Köcher, M. Wilm, T. Allen, I.W. Mattaj, V. Doye, Cell 113 (2003) 195–206.
[Published Version] View | DOI | PubMed | Europe PMC
 
[6]
2003 | Journal Article | IST-REx-ID: 11121
RanGTP mediates nuclear pore complex assembly
T.C. Walther, P. Askjaer, M. Gentzel, A. Habermann, G. Griffiths, M. Wilm, I.W. Mattaj, M. Hetzer, Nature 424 (2003) 689–694.
View | DOI | PubMed | Europe PMC
 
[5]
2002 | Journal Article | IST-REx-ID: 11124 | OA
Ran binds to chromatin by two distinct mechanisms
D. Bilbao-Cortés, M. Hetzer, G. Längst, P.B. Becker, I.W. Mattaj, Current Biology 12 (2002) 1151–1156.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
[4]
2002 | Journal Article | IST-REx-ID: 11123
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
M. Hetzer, O.J. Gruss, I.W. Mattaj, Nature Cell Biology 4 (2002) E177–E184.
View | DOI | PubMed | Europe PMC
 
[3]
2001 | Journal Article | IST-REx-ID: 11125
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly
M. Hetzer, H.H. Meyer, T.C. Walther, D. Bilbao-Cortes, G. Warren, I.W. Mattaj, Nature Cell Biology 3 (2001) 1086–1091.
View | DOI | PubMed | Europe PMC
 
[2]
2000 | Journal Article | IST-REx-ID: 11126
An Atp-dependent, Ran-independent mechanism for nuclear import of the U1a and U2b′′ spliceosome proteins
M. Hetzer, I.W. Mattaj, Journal of Cell Biology 148 (2000) 293–304.
View | DOI | PubMed | Europe PMC
 
[1]
2000 | Journal Article | IST-REx-ID: 11127 | OA
GTP hydrolysis by Ran is required for nuclear envelope assembly
M. Hetzer, D. Bilbao-Cortés, T.C. Walther, O.J. Gruss, I.W. Mattaj, Molecular Cell 5 (2000) 1013–1024.
[Published Version] View | DOI | Download Published Version (ext.) | PubMed | Europe PMC
 
Marked Publication(s)

Search

Filter Publications

    • Display / Sort

    Citation Style: Default

    Export / Embed